研究方法

11名内镜医师对30个结直肠病变的90张图像进行了评估。病灶随机选取。每个病灶3张图像由相同位置的白光(WLI)、BLI-bright和LCI图像组成。参与者凝视图像，他们的眼球运动被眼球追踪器追踪。我们分析了参与者是否能够检测到病变，以及他们需要多长时间才能检测到病变。我们评估了各种成像模式的漏检率和检测时间。

Methods: Eleven endoscopists evaluated 90 images of 30 colorectal lesions. The lesions were randomly selected. Three images of each lesion comprised white light imaging (WLI), BLI-bright, and LCI in the same position. Participants gazed at the images, and their eye movements were tracked by the eye tracker. We analyzed whether the participants could detect the lesion and how long they took to detect the lesion. We assessed the miss rate and detection time among the imaging modalities.

结果

排除1名内镜医师，评估10名内镜医师。总体而言，WLI的病灶漏诊率为12.6%，BLI-bright为6.0%，LCI为4.3%;BLI-bright和LCI的漏检率显著低于WLI (P < 0.01)，两者间差异无统计学差异(P = 0.54)。WLI、BLI-bright和LCI的平均检测时间分别为1.58 ± 1.60 s、1.01 ± 1.21 s 、1.10 ± 1.16 s。BLI-bright和LCI的检测时间明显短于WLI (P < 0.0001)，前两种模式之间无显著差异(P = 0.34)。专家与非专家之间的漏检率和检出时间，WLI有显著性差异，BLI-bright和LCI无显著性差异。

Results: One endoscopist was excluded, and 10 endoscopists were assessed. Overall, 12.6% of lesions were missed with WLI, 6.0% with BLI-bright, and 4.3% with LCI; the miss rate of BLI-bright and LCI was significantly lower than that of WLI (P < 0.01), with no significant difference between the former modalities (P = 0.54). Mean (± SD) detection times were 1.58 ± 1.60 s for WLI, 1.01 ± 1.21 s for BLI-bright, and 1.10 ± 1.16 s for LCI. Detection time for BLI-bright and LCI was significantly shorter than that for WLI (P < 0.0001), with no significant difference between the former modalities (P = 0.34). Regarding the miss rate and detection time between the expert and the non-experts, there was a significant difference with WLI but not with BLI-bright and LCI.