方法

所有检查均使用富士胶片公司LASEREO内镜系统。共招募52名UC患者，使用LCI检查评估193个区域。LCI分级被分为：A无发红；B发红，伴可见血管；C发红，无可见血管。感兴趣区域（ROIs）设置在活检部位，ROIs中的红色是根据国际照明委员会（CIE）色彩空间计算得到，并已数字化（LCI指数）。在每个ROI处取活检标本，并用Matts组织病理学分级进行评估。30个月被定义为内镜诊断和UC复发之间的时间间隔。

Methods: All examinations were carried out with a LASEREO endoscopic system [FUJIFILM Co., Tokyo, Japan]. Fifty-two patients with UC were enrolled, and 193 areas assessed by LCI were examined. LCI patterns were classified as; A, no redness; B, redness with visible vessels; and C, redness without visible vessels. Regions of interest [ROIs] were set at biopsy sites, and the red colour in the ROI was calculated from the Commission internationale de l’éclairage [CIE] color space and digitized [LCI-index]. Biopsy specimens were taken at each ROI and evaluated with Matts histopathological grade. Thirty months was defined as the time interval between endoscopic diagnosis and relapse of UC.

结果

LCI分类的观察者一致性在专家和非专家之间非常好。在Mayo内镜评分为0的区域中，41.8%和4.6%分别被定义为LCI-B和LCI-C。在Mayo内镜评分为1的区域中，60.5%和34.6%分别被定义为LCI-C和LCI-B。LCI指数与组织病理学Matts评分密切相关。无复发率与LCI分类显著相关[p=0.0055]，但与Mayo内镜评分无关[p=0.0632]。

Results: Interobserver agreement for LCI classification was excellent between an expert and non-experts. Among areas with a Mayo endoscopic subscore of 0, 41.8% and 4.6% were classified as LCI-B and LCI-C, respectively. Among areas with a Mayo endoscopic subscore of 1, 60.5% and 34.6% were classified as LCI-C and LCI-B, respectively. The LCI index strongly correlated with the histopathological Matts score. Non-relapse rates significantly correlated with LCI classification [p = 0.0055], but not with Mayo endoscopic subscore [p = 0.0632].