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联动成像技术可帮助内镜检查诊断幽门螺杆菌感染
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LCI文献
联动成像技术可帮助内镜检查诊断幽门螺杆菌感染
2022/06/06LCI文献
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联动成像技术可帮助内镜检查诊断幽门螺杆菌感染
Linked color imaging can help gastric Helicobacter pylori infection diagnosis during endoscopy
TH Chen, CM Hsu, HT Cheng, YY Chu, MY Su… - Journal of the Chinese Medical Association, 2018
LCI可以作为一种有价值的初筛工具，用于实时诊断幽门螺杆菌感染。它对幽门螺杆菌的诊断具有很高的准确性。因此，对于怀疑有幽门螺杆菌感染的患者，需要使用适当的方法仔细诊断感染，因为根据共识，应在癌前病变发展之前尽快根除它们。
Conclusions: LCI could be playing a valuable initial screen tool for real-time diagnosis of H. pylori infections. It has a high accuracy of diagnosis of H. pylori infections. Therefore, in patients suspected to have H. pylori infections using LCI, the infections need to be carefully diagnosed using appropriate methods because, as per the consensus, they should be eradicated as soon as possible before precancerous lesions develop.
01
背景
食管胃十二指肠检查（EGD）是检测黏膜和黏膜下病变的标准工具。然而，仅使用EGD鉴定幽门螺杆菌（H.P）感染的准确性有限。联动成像技术（LCI）是一种新的工具，可捕获具有足够对比度的实时图像以观察黏膜微结构。
Background: Esophagogastroduodenoscopy (EGD) is a standard tool for detection of mucosal and submucosal lesions. However, identification of Helicobacter pylori (H. P) infection using EGD alone is limited in accuracy. Linked color imaging (LCI) is a novel tool to capture real-time image with sufficient contrast to observe mucosal microstructure.
02
方法
本研究旨在评估LCI在鉴定幽门螺杆菌感染中的适用性。共招募了122名连续计划进行EGD的患者。用LCI和放大镜给他们做内镜检查。幽门螺杆菌的确认依据活检病例结果和快速尿素酶实验或尿素呼气实验。
Methods: This study aims to evaluate the applicability of LCI in the identification of H. pylori infection. Consecutive 122 patients scheduled for EGD were included. They were examined with LCI and magnifying endoscopy. The classification of H. pylori was based on pathology results of biopsy and rapid urease test or urea breath test.
03
结果
我们将基于LCI或放大内镜检查的结果跟参考的定义进行了比较。在122名患者中，36名患者有幽门螺杆菌感染（29.51%）。LCI、放大内镜以及LCI结合放大内镜对幽门螺杆菌感染的诊断准确率分别为78.38%、81.98%和78.38%。各组的敏感性和特异性分别为70.97%、81.25%、80.65%以及82.5%、83.87%、76.25%。阳性预测值分别为59.46%、64.10%和57.78%，阴性预测值分别为87.84%、91.67%和92.42%。
Results: We compared the results based on LCI or magnifying endoscopy to reference classification. Of 122 patients, 36 had H. pylori infection (29.51%). The level of accuracy of diagnosis of H. pylori infections by LCI, magnifying endoscopy, and both LCI and magnifying endoscopy was 78.38%, 81.98%, and 78.38%, respectively. The sensitivity and specificity of each group were 70.97%, 81.25%, and 80.65% and 82.5%, 83.87%, and 76.25%, respectively. The positive predictive values were 59.46%, 64.10%, and 57.78%, respectively, and the negative predictive values were 87.84%, 91.67%, and 92.42%, respectively.
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